Saxena Lab

Dissecting causal role of insomnia in cardiovascular disease

This project aims to identify genes and pathways at GWAS loci for insomnia symptoms in humans, test the consequence of loss-of-function of Drosophila orthologs on sleep and cardiac function, and test the impact of perturbed sleep on cardiovascular function in humans and Drosophila.

Co-PIs: Richa Saxena, James Walker, Girish Melkani (University of Alabama at Birmingham)

Links to Cardiometabolic Disease Research AreaGenetics of Sleep Research Area